Applications / Research

Micromachining

NS CNC machines operate in research institutions across North America, Europe, and Asia. Fabricated parts include NMR microcoils, microfluidic chips, solenoids, resonators, and micro-scale sensors. The work appears in peer-reviewed journals.

NS·CNC · Research — laboratory grade
Overview / Laboratories

NS CNC for research and development.

Research laboratory milling

High precision and rigid motion, in use since 2017.

Our machines have operated for years in university laboratories worldwide, supporting research across biology, chemistry, electronics, and physics. High precision, reliable motion, spindle runout under 1 micron — the foundation scientists depend on to fabricate custom components, develop new methods, and publish original work.

Application / Microfluidics

Channels measured in micrometers.

Microfluidic chip fabrication

Clean edges in plastic, without melting or delamination.

The Simpson group at the University of Toronto and Professor Ronnie Willaert's laboratory at VUB Brussels fabricate microfluidic chips on NS CNC machines. Channel milling measured in micrometers requires sustained positional accuracy across long programs, a rigid machine base, minimal spindle runout, and very high spindle speed.

milled microfluidic channel — section viewup to 60,000 rpmcutters down to 5 µm diaw · µmd · µmclean top edge — no burrflat floorvertical walls — no melting,no delaminationchannel width and depth measured in micrometers
Channel cross-section — edge and wall quality

In section: vertical walls, a flat floor, clean edges.

In cross-section, a milled channel shows vertical walls, a flat floor, and clean top edges — the result of high spindle speed, runout under 1 micron, and a rigid base. Channel width and depth are both in the micrometer range.

The chips in the photos below were fabricated on NS CNC machines in research laboratories; the publications section lists the journals where this work appears.

Field / University of Toronto

Simpson Research Group — 4- and 5-axis NS CNC machines, in operation since 2017.

Professor Andre Simpson’s laboratory at the University of Toronto has been using several NS CNC milling machines — 4- and 5-axis, with spindles and laser — to fabricate NMR coils, resonators, and microfluidic components for published research.

Simpson Research Group, University of Toronto
Professor Andre Simpson examines the first milled copper spiral coils on the Mira 6. September 2017

Several high-precision NS CNC machines, in use since 2017.

The coils, resonators, and microfluidic components shown here were milled on these machines and documented in the group's published research.

www.utsc.utoronto.ca/labs/asimpson

16-turn spiral coil

16-turn spiral coil

A 16-turn spiral coil with a 1.5 mm outer diameter was milled from Copper-coated Teflon.

16-turn spiral coil

16-turn spiral coil

Both the turns/wires and the spacing between them are 0.02 mm wide.

3-turn microcoil

3-turn microcoil

A 3-turn microcoil with a 1 mm inner diameter was milled from Copper-coated Teflon. Both the turns/wires and the spacing between them are 50 µm wide.

Slotted tube resonator

Slotted tube resonator

Shown is a Slotted Tube Resonator milled from a copper pipe with an 1.270 mm outer diameter and an 0.813 mm inner diameter. Each strip is 7 mm long and is spaced 0.8 mm apart. The slotted tube resonator was soldered onto a specially designed circuit board that was milled from Copper-coated Teflon.

Microstrips

Microstrips

Two 1 mm X 9 mm microstrips (with a built-in 2 mm wide, 7 mm long, and 1.58 mm deep sample chamber behind the microstrip) are shown.

Double-sided microstrips

Double-sided microstrips

Parts of two 1 mm X 5 mm double-sided microstrips were milled from an FR1 PCB Board and soldered together. Acrylic inserts containing microfluidic channels (that will contain the sample) were milled from an acrylic rod and used to introduce the sample between each strip. One is designed to keep larger mass-limited samples between the two microstrips (top) while the other contains only microfluidic channels and is intended for liquid samples (bottom). All components were machined on a Mira-6.

Solenoid

Solenoid

The Solenoid was made from a 6.4 mm Diameter Copper coated Acrylic Rod, made on Mira 6.

Microstrip

Microstrip

The front of a 3 mm long and 0.15 mm wide microstrip (made from copper-coated Teflon) is shown. The microstrip contains a built-in 1 mm wide, 3 mm long, and 1.58 mm deep sample chamber on the opposing side (shown in next photo).

Laser engraving — Mira 7L

Laser engraving — Mira 7L

5 axis NS CNC laser machine Mira 7L to do high precision engraving on metal.

Laser engraving — Mira 7L

Laser engraving — Mira 7L

Letter height 0.1 mm.

Elara with granite base

Elara with granite base

Professor Andre Simpson next to his latest 4 axis NS CNC ELARA mill with a granite base. December 2022.

Elara with granite base

Elara with granite base

Field / VUB · Belgium

Professor Ronnie Willaert from the Vrije Universiteit Brussel, Belgium

Professor Ronnie Willaert

The CNC Elara as a fast-prototyping method.

Professor Ronnie Willaert (Vrije Universiteit Brussel, Brussels, Belgium) specializes in yeast research (Saccharomyces cerevisiae, Candida albicans, and C. glabrata) and single-molecule biophysics.

His work covers optical nanomotion detection and biofabrication, including microfluidic-chip and micropattern development. He develops micro- and nanobiotechnological techniques to study bone and yeast cells in microgravity aboard the International Space Station, in research projects funded by the European Space Agency (ESA) and the Belgian Science Policy Office (Belspo).

Currently, he is using the CNC Elara (NS CNC) as a fast-prototyping method to optimize a microfluidic chip that will be used for the ESA project “FLUMIAS Yeast Nanomotion”, where yeast cellular nanomotion will be used to assess the effect of antifungals on the viability of yeast cells in space conditions (ISS).

Research Group Structural Biology Brussels (SBB)

Alliance Research Group VUB-UGent “NanoMicrobiology” (NAMI)

International Joint Research Group VUB-EPFL (Switzerland) “BioNanotechnology & NanoMedicine” (NANO)

Vrije Universiteit BrusselEuropean Space AgencyNANO — BioNanotechnology & NanoMedicine
Research / Publications

Publications

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